Post cycle therapy PCT information - Anabolic steroids, fitness and bodybuilding discussion and information forums

T_man · 12-16-2007, 07:22 PM

Post cycle therapy (PCT)

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After a steroid user has finished a cycle his natural production of hormones particularly testosterone is suppressed and needs to be restore to its original state quickly to minimise some of the post cycle side effects such as depression and loss in strength and weight. Post cycle therapy is an after cycle drug regime which is designed to do this and is in my opinion more important from the cycle itself. I would rather be moderately big and my balls still work then look like the hulk and have pea sized nuts.

The 2 main drugs used for PCT are Tamoxifen (nolvadex) and Clomid. There are others but these two are considered to be the best.

Clomid and Nolvadex are both anti-estrogens belonging to the same group of triphenylethylene compounds. They are structurally related and specifically classified as selective estrogen receptor modulators (SERMs) with mixed agonistic and antagonistic properties. This means that in certain tissues they can block the effects of estrogen, by altering the binding capacity of the receptor, while in others they can act as actual estrogens, activating the receptor.
In men, both of these drugs act as anti-estrogens in their capacity to oppose the negative feedback of estrogens on the hypothalamus and stimulate the heightened release of GnRH (Gonadotropin Releasing Hormone). LH output by the pituitary will be increased as a result, which in turn can increase the level of testosterone by the testes.
Both drugs do this, but for some reason bodybuilders persist in thinking that Clomid is the only drug good at stimulating testosterone. What you will find with a little investigation however is that not only is Nolvadex useful for the same purpose, it should actually be the preferred agent of the two.

PCT Protocol

The normal protocol for clomid is:
day 1 300mg
day 2-11 100mg ed (every day)
day 12-21 50 mg ed
Doses split throughout the day.

This should be followed by a significant time off of steroids to allow the body to recover. The rule is that a cycle should not be started with out the PCT material as if you have to cut a cycle short for any reason you can still recover.

When PCT should be started all depends on the half-life of the substance. The half-life is the time it takes the substance to break down by half. Testosterone enthanate has a halflife of about 2 weeks so it is suggested this is when the PCT should begin. If started before hand the Test will still be in your system and still suppressing your natural levels so PCT would have little effect. Dianabol on the other hand had a very short half life so PCT can be started the day after the last dose.

For more information on the steroids half-life then please re read the profiles and that should answer your questions. On the next page is a table containing recommended start times for PCT after each steroid. If you are doing a stack then it is best to pick the one with the longest PCT start time before commencing with your PCT protocol.

Anadrol50/Anapolan50: 8 - 12 hours
Deca durabolan: 3 weeks
Dianabol: 4 - 8 hours
Equipoise: 17 - 21 days
Finajet/Trenbolone: 3 days
Primabolan depot: 10 - 14 days
Sustanon: 3 weeks
Testosterone Cypionate: 2 weeks
Testosterone Enanthate: 2 weeks
Testosterone Propionate: 3 days
Testosterone Suspension: 4 - 8 hours
Winstrol 8 - 12 hours

For example if you were to do a Test / Dianabol cycle then you would start PCT 2 weeks after your last test injection as it is the longest acting steroid in your cycle.

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T_man · 12-16-2007, 07:23 PM

Clomid

Clomid is not an anabolic/androgenic steroid. Since it is a synthetic estrogen it belongs, however, to the group of sex hormones. In school medicine Clomid is normally used to trigger ovulation. Clomid also has a strong influence on the hypothalamohypophysial testicular axis. It stimulates the hypo-physis to release more gonadotropin so that a faster and higher release of FSH (follicle stimulating hormone) and LH (luteinising hormone) occurs. This results in an elevated endogenous (body's own) testosterone level. Clomid is especially
effective when the body's own testosterone production, due to the intake of anabolic/androgenic steroids, is suppressed. In most cases Clomid can normalize the testosterone level and the spermatogenesis (sperm
development) within 10- 14 days. For this reason Clomid is primarily taken after steroids are discontinued. At this time it is extremely important to bring the testosterone production to a normal level as quickly as possible
so that the loss of strength and muscle mass is minimized. Even better results can be achieved if Clomid is combined with HCG or when Clomid is used after the intake of HCG.

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Paradoxically, although Clomid is a synthetic estrogen it also works as an antiestrogen. The reason is that Clomid has only a very low estrogenic effect and thus the stronger estrogens which, for example, form during
the aromatization of steroids, are blocked at the receptors. These would include those that develop during the aromatizing of steroids. This does not prevent the steroids from aromatizing but the increased estrogen is
mostly deactivated since it cannot attach to the receptors. The increased water retention and the possible signs of feminization can thus be reduced or even completely avoided. Since the antiestrogenic effect of Clomid is lower than those found in Proviron, Nolvadex, and Teslac it is mainly taken as a testosterone stimulant. Clomid is a medication that promotes the production of the body's own stimulating hormone, gonadotropin, which in turn increases the testosterone level. It is, for example, administered to women as a
so-called antiestrogen to trigger ovulation ("ovulation stimulator").

Side effects of Clomid are very rare if reasonable dosages are taken. Possible side effects are climacteric hot flashes and occasional visual disturbances which can manifest themselves in blurred vision, giving flickering or
flashing. Should visual disturbances occur, the manufacturer recommends discontinuing Clomid treatment. Inadequate liver functions cannot be excluded; however, they are very unlikely. In women enlargement of the
ovaries and abdominal pain can occur since Clomid stimulates the ovaries. When taking Clomid multiple pregnancies are possible as well. As for the dosage, 50-100 mg/day (1 -2 tablets) seems to be sufficient. The
tablets are usually taken with fluids after meals. If several tablets are taken it is recommended that they be administered in equal doses distributed through-out the day. The duration of intake has been rumoured to not be taken for longer than 10-14 days. This is incorrect. Clinical studies with male patients have shown clomid to be used for up to a year or longer. Most athletes begin with 100 mg/day, taking one 50 mg tablet every morning and evening after meals. After the fifth day the dosage is often reduced to only one 50 mg tablet per day It is normally not necessary to take the compound for more than ten days in order to increase the endogenous testosterone production. Clomid is relatively expensive. A package with 10 tablets costs approx. $35 - 45 on the black market.

T_man · 12-16-2007, 07:23 PM

Nolvadex

This remedy is somewhat different from others since it is not an anabolic/androgenic steroid. For male and female bodybuilders, how-ever, it is a very useful and recommended compound which is con-firmed by its widespread use and mostly positive results. Nolvadex belongs to the group of sex hormones and is a so-called antiestrogen. The normal application of Nolvadex is in the treatment of certain forms of breast cancer in female patients. With Nolvadex it is pos-sible to reverse an existing growth process of deceased tissue and prevent further growth. The growth of certain tissues is stimulated by the body's own estrogen hormone. This is especially true for the breast glands in men and women since the body has a large number of estrogen receptors at these glands which can bond with the estro-gens present in the blood. If the body's own estrogen level is unusually high an undesired growth of breast glands occurs. However, in healthy women and
particularly in men this is not the case. Despite this, it is mostly male bodybuilders who use Nolvadex, and fewer women. At first sight this seems somewhat inconceivable but when taking a closer look, the reasons are
clear. Bodybuilders who take Nolvadex also use anabolic steroids at the same time. Since most steroids aromatize more or less strongly, i.e. part of the substance is converted into estrogens, male bodybuilders can experience a significant elevation in the normally very low estrogen level. This can lead to feminization symptoms such as gynecomastia (growth of breast glands), increased fat deposits and higher water retention.

The antiestrogen Nolvadex works against this by blocking the es-trogen receptors of the effected body tissue, thereby inhibiting a bonding of estrogens and receptor. It is, however, important to un-derstand that Nolvadex
does not prevent the aromatization but only acts as an estrogen antagonist. This means that it does not prevent testosterone and its synthetic derivatives (steroids) from converting into estrogens but only fights with them in a sort of "competition" for the estrogen receptors. This characteristic has the disadvantage that after the discontinuance of Nolvadex a "rebound effect" can occur which means that the suddenly freed estrogen receptors are now able to absorb the estrogen present in the blood. For this reason the combined intake of Proviron is suggested (see Proviron.) Nolvadex is also useful during a diet since it helps in the burning of fat. Al-though Nolvadex has no direct fatburning effect its antiestrogenic effect contributes to keeping the estrogen
level as low as possible. Nolvadex should especially be taken together with the strong androgenic steroids Dianabol and Anadrol 50, and the various test-osterone compounds. Athletes who have a tendency to retain
water and who have a mammary dysfunction should take Nolvadex as a prevention during every steroid intake. Since Nolvadex is very affective in most cases it is no wonder that several athletes can take Anadrol 50
and Dianabol until the day of a competition, and in combination with a diuretic still appear totally ripped in the. limelight. Those who already have a low body fat content will achieve a visibly improved muscle hardness with Nolvadex.

Several bodybuilders like to use Nolvadex at the end of a steroid cycle since it increases the body's own testosterone production. Nolvadex is cheap and easy to obtain online.

T_man · 02-22-2008, 09:11 PM

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T_man · 02-23-2008, 04:54 AM

A list of good Post Cycle Therapy Threads

PCT Protocol
The inhibition and recovery of natural testosterone levels
The post cycle therapy information thread
Nolvadex vs Clomid
Clomid FAQ

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T_man · 03-09-2008, 01:36 AM

If you are looking for a selection of PCT supplements then we are going to list a few here which we have tried and like. They are ideal for after a prohormone or steroid cycle to compliment PCT or if clomid or nolvadex is not availiable for some reason.

T_man · 03-09-2008, 01:38 AM

Post cycle therapy designed to restore the delicate hormonal balance and prevent muscle loss after any hormonal anabolic cycle.

FACT: You hormones are completely out of balance during and after any anabolic cycle, and in many cases your body is no longer producing normal levels of its own natural testosterone potentially leading to losses in muscle and libido.

This imbalance is actually a good thing while on cycle, as it indicates the cycle is probably working to promote muscle gain! But after the cycle, the lack of natural testosterone production is one of the biggest reasons people lose their hard earned gains and may have a difficult time promptly recovering their libido. Advanced PCT is designed for one purpose, to get your testosterone back to normal and natural production as quickly yet gently as possible.

The common post cycle advice is to jack up natural testosterone levels by squashing estrogen production/conversion. This fails to recognize that hormone levels are in a very dynamic balance, regulated by complex mechanisms(1), and that every change in hormone status has an inverse and sometimes drastic reaction. Advanced PCT was designed by looking at the complete picture of the body’s reaction at the end of a hormonal muscle building cycle to create a product that greatly assists the body in returning to its self-regulating, delicate hormonal balance to minimize muscle loss and estrogen related side effects.

When you take any externally supplied hormone, it will cause a positive imbalance of your body’s natural hormones while on cycle and a negative imbalance when transitioning off cycle. To understand how important and absolutely necessary PCT is to any hormonal cycle we need to briefly understand what happens in the body while on cycle. The purpose in taking any pro-hormone, steroid, or hormone is to cause protein synthesis by directly activating androgen receptors. Testosterone is the natural key to unlocking these powerful receptors, but other synthetic or naturally occurring compounds have been found to do this quite successfully, such as 3-AD. Most work by either directly converting to testosterone or are chemically very similar to testosterone in structure, which means they also participate in the body’s natural self regulation of testosterone production(2).

Self regulation? Yes, the body produces various hormones (testosterone activators)(3), that cause testosterone to be secreted, while at the same time the testosterone itself stops or slows the production of these hormones(4). The end result is a perfect balance of testosterone levels. So when we introduce an external testosterone or testosterone equivalent, those activators stop producing for awhile, thus significantly reducing natural testosterone secretion(5). So in reality, when you quit your cycle, what your body immediately needs is to quickly start producing these testosterone activators more than anything because they control the release of testosterone. They are the gate keepers! But, this is only part of the equation.

Hormone levels want to be in a precise balance, which includes the testosterone /estrogen balance. Many pro-hormones claim that their products cannot aromatize, thus leading you to a conclusion that you do not need to worry about estrogen. However, the body wants to be in balance and when the testosterone levels skyrocket while on-cycle you must recognize that your body reacts to create balance by increasing natural estrogen production(6). Excess estrogen can interrupt the production of testosterone and cause unwanted effects in healthy males(7). Again the key is balance and your body needs some estrogen. Many commonly used post cycle products work by completely eradicating estrogen from the body. This is far from supporting the delicate balance in the body. Choose a product that will get you back to normal, safely and quickly. Choose a product that focuses on the whole picture to avoid other negative reactions. Choose Anabolic Xtreme Advanced PCT.

Every ingredient was carefully researched, tested, and integrated in precise ratios to create the new standard for post cycle therapy products. Advanced PCT will propel your hormones back to healthy levels quickly, allowing you to keep those hard earned gains and avoid the effects of the body’s reaction to the end of an anabolic cycle. For additional protection against other non-hormonal post cycle factors that can affect muscle retention, see Anabolic Xtreme Retain2 and add it to your post cycle regimen.

General Precautions and Considerations
It is not uncommon for novice users to enjoy the benefits of an anabolic cycle to the point that they don’t want to stop. It is very important for you to give your body a chance to recover and return to normal hormonal production before starting an additional cycle. As with any product that affects hormone levels you want to give your body a break and Advanced PCT is no exception. The product is designed to assist your body in returning to normal hormonal balance. After that is accomplished, typically four weeks, we recommend refraining from taking any hormonal affecting products for at least one month.

Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 90
Amount Per Serving:
6-Bromoandrostenedione 25mg
Cordyceps sinensis concentrate (20% Polysaccarides) 450mg
L-Histidine HCL 100mg
Grape seed extract (95% Procyanidolic oligomers) 50mg

Suggested Use
Take 1-3 capsules nightly. Do not exceed 8 weeks of continuous use

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